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| Measuring Multiple Endpoints in One Step | |
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| Exposure to a test substance can cause toxicity such as DNA damage or apoptosis. The MultiFlow™ family of kits provides a platform for quickly detecting this information. These kits were developed from the ground up to be simple and efficient. With this method, you can now liberate nuclei, stain nucleic acids, and label nuclear epitopes all in the same step. After a brief incubation period, samples are ready for flow cytometric analysis. | |
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| Features | | Benefits | |
| - One Step, Multiple Endpoints
Flexible method addresses different pathways and events. - Low Compound Requirements
Perform analyses in 96-well plates. Add-and-read format lyses cells and stains nuclei in one step. - QC’d Kits, Unlimited Technical Support
Everything you need to successfully perform the method is included in the box or available for download!
| | - Easy to Use Multiplexed Assay
High information content yields Mode of Action data. - Place Anywhere In Your Pipeline
Use as a screening tool or a follow up to a positive result. - Fast Results, Reliable Data
Speed up your work with efficient, rapid processing and analysis. Speak with the scientists who developed this method. Send plots, email, or call with questions! | |
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| Article Selected as Editor's Choice
Litron's recent paper in Environmental & Molecular Mutagenesis is available as Open Access.
This article describes the interlaboratory validation of our new high information content MultiFlow assay.
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Unlimited Technical Support
Speak with the scientists who designed the method • Unlimited phone and email technical support (send us your plots!) • Training, at your site or ours
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| Single Antibody Kits | | Multiple Antibody Kits | |
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| Each single antibody kit provides cell density, proliferation and cytotoxicity information. Additionally, they measure: Double-stranded DNA breaks using γH2AX • Genotoxic stress using p53 • Mitotic cells using phospho-histone H3 • Apoptosis using cleaved-PARP • More kits under development | | Each multiple antibody kit provides cell density, proliferation and cytotoxicity information. Additionally, they provide: p53, γH2AX, and phospho-histone H3 (for detection of genotoxic stress, double-stranded DNA breaks, and mitotic cells) • Cleaved-PARP, γH2AX and phospho-histone H3 (for detection of apoptosis, double-stranded DNA breaks, and mitotic cells) | |
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| Available Kits | |
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| In Vitro MultiFlow Kits | | Product ID | | Applications | |
| MultiFlow® - cleaved PARP | | MultiFlow (Cleaved PARP) | |
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| MultiFlow® - γH2AX | | MultiFlow (γH2AX) | | | |
| MultiFlow® - phospho-histone H3 | | MultiFlow (H3) | | | |
| MultiFlow® - p53 | | MultiFlow (p53) | | | |
| MultiFlow® - cleaved PARP, γH2AX, phospho-histone H3 | | MultiFlow (PARP, γH2AX, H3) | | DNA Damage Response Genotoxic Mode of Action
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| MultiFlow® - p53, γH2AX, phospho-histone H3 | | MultiFlow (p53, γH2AX, H3) | | DNA Damage Response Genotoxic Mode of Action
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| MultiFlow® - p53, γH2AX, phospho-histone H3, cleaved PARP | | MultiFlow (p53, γH2AX, H3, PARP) | | DNA Damage Response Genotoxic Mode of Action Apoptosis
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| ◆ 모든 MultiFlow Kit는 384 sample 용 입니다. | |
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(주)코메드 ㅣ 경기도 성남시 중원구 둔촌대로 555 선일테크노피아 805호 Email. service@kormed.com l Tel. 031-777-3101 l Fax. 031-777-3999 |