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In Vitro MultiFlow® Kits 2020/03/12 (11:33) 조회(1270) 관리자

 


 

 

 

 

 

 

 



 

 

 

 

 

 

 

 

Measuring Multiple Endpoints in One Step

 

 

 

 

 

 

 

 

 

Exposure to a test substance can cause toxicity such as DNA damage or apoptosis. The MultiFlow™ family of kits provides a platform for quickly detecting this information.

 

These kits were developed from the ground up to be simple and efficient. With this method, you can now liberate nuclei, stain nucleic acids, and label nuclear epitopes all in the same step. After a brief incubation period, samples are ready for flow cytometric analysis. 

 

 

 

 

 

 

 

 

 


 

 

 

 

 

 

 

 

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Features

 

Benefits

 

 

  • One Step, Multiple Endpoints

Flexible method addresses different pathways and events.

  • Low Compound Requirements

Perform analyses in 96-well plates.

  • No Washes Required

Add-and-read format lyses cells and stains nuclei in one step.

  • QC’d Kits, Unlimited Technical Support

Everything you need to successfully perform the method is included in the box or available for download!

 

 

  • Easy to Use Multiplexed Assay

High information content yields Mode of Action data.

  • Place Anywhere In Your Pipeline

Use as a screening tool or a follow up to a positive result.

  • Fast Results, Reliable Data

Speed up your work with efficient, rapid processing and analysis.

  • Feel Confident

Speak with the scientists who developed this method. Send plots, email, or call with questions!

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Article Selected as Editor's Choice


Litron's recent paper in Environmental & Molecular Mutagenesis is available as Open Access.


This article describes the interlaboratory validation of our new high information content MultiFlow assay.


 


 

 


Unlimited Technical Support


Speak with the scientists who designed the method

Unlimited phone and email technical support (send us your plots!)

Training, at your site or ours

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Single Antibody Kits

 

Multiple Antibody Kits

 

 

 

 

 

 

 

 

 

Each single antibody kit provides cell density, proliferation and cytotoxicity information.

 

Additionally, they measure:

 

Double-stranded DNA breaks using γH2AX


Genotoxic stress using p53

Mitotic cells using phospho-histone H3

Apoptosis using cleaved-PARP

More kits under development

 

 

Each multiple antibody kit provides cell density, proliferation and cytotoxicity information.

 

Additionally, they provide:

 

p53, γH2AX, and phospho-histone H3 (for detection of genotoxic stress, double-stranded DNA breaks, and mitotic cells)

Cleaved-PARP, γH2AX and phospho-histone H3 (for detection of apoptosis, double-stranded DNA breaks, and mitotic cells)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 Available Kits

 

 


 


 

 

 

 

In Vitro MultiFlow Kits

 

Product ID

 

Applications 

 

 

MultiFlow® - cleaved PARP

 

 

MultiFlow (Cleaved PARP)

 

  • Apoptosis

 

 

MultiFlow® - γH2AX

 

 

MultiFlow (γH2AX)

 

 

  • Double Strand DNA Breaks

 

 

 

MultiFlow® - phospho-histone H3

 

MultiFlow (H3)

 

  • Mitotic Cells

 

 

MultiFlow® - p53

 

MultiFlow (p53)

 

  • Genotoxic Stress

 

 

MultiFlow® - cleaved PARP, γH2AX, phospho-histone H3

 

 

MultiFlow (PARP, γH2AX, H3)

 

  • DNA Damage Response
  • Genotoxic Mode of Action

 

 

MultiFlow® - p53, γH2AX, phospho-histone H3

 

 

 

MultiFlow (p53, γH2AX, H3)

 

 

  • DNA Damage Response
  • Genotoxic Mode of Action

 

 

MultiFlow® - p53, γH2AX, phospho-histone H3, cleaved PARP

 

 

MultiFlow (p53, γH2AX, H3, PARP)

 

 

  • DNA Damage Response
  • Genotoxic Mode of Action
  • Apoptosis

 

 

◆ 모든 MultiFlow Kit는 384 sample 용 입니다.

 

 

 

 

 

 

 

 

 

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