Mesenchymal Stem Cells (MSC), also known as marrow stromal cells, are a self renewing population of multipotent cells present in bone marrow and many other adult tissues. MSC can be isolated from bone marrow by adherence to plastic and can differentiate into multiple lineage-specific cells that form bone, fat, cartilage, muscle, and tendon. Trevigen's RMSC are provided as a frozen ampoule containing 1 x 106 passage 3 cells. These cells can be maintained in an undifferentiated state when grown in Trevigen's Qualified RMSC Medium supplemented with RMSC Qualified FBS or induced to differentiate into adipogenic or osteogenic phenotype when growth media are supplemented with reagents contained in Trevigen's differentiation kits. Trevigen's RMSC can undergo 10 doublings without alteration in cell morphology or differentiation potential.
Features: Primary mesenchymal stem cells isolated from rat bone marrow by adhesion and purified by successive passages.
Applications: Therapeutic and basic research, including transplantation studies and studies examining the repair of cardiac tissue, bone, cartilage, and tendons often using 3-D matrices.
